| Identification | Back Directory | [Name]
4-(ChloroMethyl)-5,7-dihydroxy-2H-chroMen-2-one | [CAS]
809234-33-1 | [Synonyms]
DNA polymerase-IN-1
4-chloromethyl-5,7-dihydroxy-chromen-2-one
4-(ChloroMethyl)-5,7-dihydroxy-2H-chroMen-2-one
2H-1-Benzopyran-2-one, 4-(chloromethyl)-5,7-dihydroxy- | [Molecular Formula]
C10H7ClO4 | [MDL Number]
MFCD09910544 | [MOL File]
809234-33-1.mol | [Molecular Weight]
226.61 |
| Chemical Properties | Back Directory | [Melting point ]
243-245 °C(Solv: ethanol (64-17-5)) | [Boiling point ]
499.7±33.0 °C(Predicted) | [density ]
1.569±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [pka]
7.01±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
DNA polymerase-IN-1 (compound 2d) is a DNA polymerase inhibitor (IC50=20.7 μM) with antiproliferative activity against tumor cells[1]. | [References]
[1] Bruna-Haupt EF, et al. Synthesis of Structurally Related Coumarin Derivatives as Antiproliferative Agents. ACS Omega. 2023 Jul 13;8(29):26479-26496. DOI:10.1021/acsomega.3c03181 |
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| Company Name: |
BePharm Ltd
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| Telephone: |
400-685-9117 |
| Website: |
www.bepharm.com |
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