| Identification | Back Directory | [Name]
2-Chloroadenosine hemidydrate | [CAS]
81012-94-4 | [Synonyms]
2-CADO
2-CL-ADO
2-Chloroadensoine
2-CADO, HEMIHYDRATE
2-CHLOROADENOSINE HEMIDYDRATE
2-CHLOROADENOSINE HEMIHYDRATE
2-CHLORO-D-ADENOSINE, HEMIHYDRATE
2-Chloroadenosine hemihydrate,97%
6-AMINO-2-CHLOROPURINE RIBOSIDE HEMIHYDRATE
2-Chloroadenosine hemihydrate6-Amino-2-chloropurine riboside | [EINECS(EC#)]
205-678-3 | [Molecular Formula]
C10H14ClN5O5 | [MDL Number]
MFCD00149351 | [MOL File]
81012-94-4.mol | [Molecular Weight]
319.7 |
| Questions And Answer | Back Directory | [Uses]
2-Chloroadenosine can effectively inhibit the expression of tumor metastasis-related genes mtal and mRNA, and has inhibitory effects on various cancer cells. For example, it inhibits the in vitro invasion of highly metastatic human ovarian cancer cells HO-8910PM and the growth of human prostate cancer cells. 2-Chloroadenosine can also significantly increase spinal cord blood flow after injury, thereby improving post-injury neurological function. Furthermore, it is an important pharmaceutical intermediate; it can be used as a raw material to synthesize the anti-leukemia drug cladribine (2-chlorodeoxyadenosine). |
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