| Identification | Back Directory | [Name]
CGP 20376 | [CAS]
81059-04-3 | [Synonyms]
CGP 20376
3-[(2-tert-Butyl-5-methoxybenzothiazol-6-yl)amino(thiocarbonyl)thio]propanoic acid
3-[[[(2-tert-Butyl-5-methoxybenzothiazol-6-yl)amino](thiocarbonyl)]thio]propanoic acid
Propanoic acid, 3-[[[[2-(1,1-dimethylethyl)-5-methoxy-6-benzothiazolyl]amino]thioxomethyl]thio]- | [Molecular Formula]
C16H20N2O3S3 | [MOL File]
81059-04-3.mol | [Molecular Weight]
384.54 |
| Hazard Information | Back Directory | [Uses]
CGP-20376, a 5-methoxyl-6-dithiocarbamic-S- (2-carboxy-ethyl) ester derivative of Benzothiazole (HY-W012634), is an orally active and potent antifilarial drug. CGP-20376 has anthelmintic activity[1][2]. | [References]
[1] J W Mak, et al. Antifilarial activity of CGP 20376 against subperiodic Brugia malayi in the leaf-monkey Presbytis cristata. Trop Med Parasitol. 1990 Mar;41(1):10-2. PMID:2339241
[2] P Weber. Effects of the two new anthelmintic agents CGP 6140 and CGP 20376 on adult Paragonimus uterobilateralis in the experimental host Sigmodon hispidus. Trop Med Parasitol. 1987 Dec;38(4):335-6. PMID:3327145 |
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