| Identification | Back Directory | [Name]
YC-137 | [CAS]
810659-53-1 | [Synonyms]
YC-137
L-Methionine, N-(methoxycarbonyl)-,4-[(4,9-dihydro-4,9-dioxonaphtho[2,3-d]thiazol-2-yl)amino]phenyl ester | [Molecular Formula]
C24H21N3O6S2 | [MDL Number]
MFCD22581252 | [MOL File]
810659-53-1.mol | [Molecular Weight]
511.57 |
| Chemical Properties | Back Directory | [density ]
1.442±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMSO: 5mg/mL
ethanol: 5mg/mL | [form ]
solid | [pka]
10.57±0.46(Predicted) | [color ]
red | [InChIKey]
SFDSXIZFOOBDMC-UHFFFAOYSA-N | [SMILES]
[s]1c2c(nc1Nc4ccc(cc4)OC(=O)C(NC(=O)OC)CCSC)C(=O)c3c(cccc3)C2=O |
| Hazard Information | Back Directory | [Uses]
Bcl-2 Inhibitor II, YC137 is a naphthoquinone inducer of apoptosis. | [Biological Activity]
Cell permeable: yes''Product does not compete with ATP.''Reversible: no''Target Ki: 1.3 μM in binding Bcl-2 | [IC 50]
Bcl-2: 1.3 μM (Ki); Bcl-xL: >100 μM (Ki) |
|
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|