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81167-16-0

81167-16-0 Structure

81167-16-0 Structure
IdentificationBack Directory
[Name]

IMILOXAN HYDROCHLORIDE
[CAS]

81167-16-0
[Synonyms]

CS-1140
RS 21361
Imiloxan
ImiloxanHCl
RS 21361 HYDROCHLORIDE
IMILOXAN HYDROCHLORIDE
2-(1-Ethyl-2-indazoyl)methyl-1,4-benzodioxanhydrochloride
2-(1-Ethyl-2-indazoyl)methyl-1,4-benzodioxanehydrochloride
2-(1-ETHYL-2-IMIDAZOYL)METHYL-1,4-BENZODIOXAN HYDROCHLORIDE
2-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-ethyl-1H-imidazole
1H-Imidazole, 2-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-1-ethyl-
2-(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)-1-(1-ethyl-1H-imidazol-2-yl)ethanone
2-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2YL)METHYL]-1-ETHYL-1H-IMIDAZOLE HYDROCHLORIDE
2-(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)-1-(1-ethyl-1H-imidazol-2-yl)ethanone hydrochloride
RS 21361, 2-[(2,3-dihydro-1,4-benzodioxin-2yl)methyl]-1-ethyl-1H-imidazole hydrochloride
[Molecular Formula]

C14H16N2O2
[MDL Number]

MFCD00865964
[MOL File]

81167-16-0.mol
[Molecular Weight]

244.29
Chemical PropertiesBack Directory
[Melting point ]

170 - 172°C
[Boiling point ]

411.7±24.0 °C(Predicted)
[density ]

1.22±0.1 g/cm3(Predicted)
[storage temp. ]

Desiccate at RT
[solubility ]

H2O: 30 mg/mL, soluble
[form ]

solid
[pka]

7.24±0.31(Predicted)
[color ]

white
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Antidepressant.
[Uses]

Imiloxan Hydrochloride is an α2-?adrenoceptor antagonist.
[Definition]

ChEBI: 2-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-ethylimidazole is a benzodioxine.
[Biological Activity]

A moderately potent, but highly selective α 2 -adrenoceptor antagonist, the only reported selective antagonist at the α 2B -adrenoceptor not having potent α 1 -adrenoceptor antagonist activity.
Spectrum DetailBack Directory
[Spectrum Detail]

IMILOXAN HYDROCHLORIDE(81167-16-0)1HNMR
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