ChemicalBook--->CAS DataBase List--->81189-92-6

81189-92-6

81189-92-6 Structure

81189-92-6 Structure
IdentificationBack Directory
[Name]

ACETYLLOVASTATIN
[CAS]

81189-92-6
[Synonyms]

ACETYLLOVASTATIN
Butanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-(acetyloxy)tetrahydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl ester, (2S)-
[Molecular Formula]

C26H38O6
[MDL Number]

MFCD09038917
[MOL File]

81189-92-6.mol
[Molecular Weight]

446.58
Chemical PropertiesBack Directory
[Boiling point ]

568.9±50.0 °C(Predicted)
[density ]

1.12±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: ≥ 250 mg/mL (559.81 mM)
[form ]

Solid
[color ]

White to off-white
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
Hazard InformationBack Directory
[Uses]

Acetyllovastatin, a acetate of Lovastatin, presentes a moderate inhibitory effect against the enzyme acetylcholinesterase with an IC50 of 79 μg/mL. Lovastatin has been found to display antifungal activity, and suppresses proliferation of a number of transformed cell lines[1].
[References]

[1] Cazar, et al. Antimicrobial Butyrolactone I Derivatives from the Ecuadorian Soil Fungus Aspergillus terreus Thorn. var terreus. World Journal of Microbiology and Biotechnology, 2005,21(6-7), 1067–1075.
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