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81202-00-8

81202-00-8 Structure

81202-00-8 Structure
IdentificationBack Directory
[Name]

L-GLUTAMIC ACID (5-13C)
[CAS]

81202-00-8
[Synonyms]

L-GLUTAMIC-5-13C ACID
(5-13C)-L-Glutamic acid
L-GLUTAMIC ACID (5-13C)
L-GLUTAMIC-5-13C ACID 99 ATOM % 13C
[Molecular Formula]

C5H9NO4
[MDL Number]

MFCD00144591
[MOL File]

81202-00-8.mol
[Molecular Weight]

148.14
Chemical PropertiesBack Directory
[Melting point ]

205 °C (dec.)(lit.)
[form ]

solid
[Optical Rotation]

[α]25/D +31.0°, c =2 in 5 M HCl
[InChI]

1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1/i4+1
[InChIKey]

WHUUTDBJXJRKMK-MYXYCAHRSA-N
[SMILES]

N[C@@H](CC[13C](O)=O)C(O)=O
[CAS Number Unlabeled]

56-86-0
Safety DataBack Directory
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

L-Glutamic acid-5-13C is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
[IC 50]

NMDA Receptor
[References]

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
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