| Identification | Back Directory | [Name]
(D-ALA4)-SUBSTANCE P (4-11) | [CAS]
81381-50-2 | [Synonyms]
(D-ALA4)-SUBSTANCE P (4-11)
Substance P, fragment 4-11, (D-Ala4)
D-ALA-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2
H-D-ALA-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2
SUBSTANCE P OCTAPEPTIDE D-ALA-4-FRAGMENT 4-11)
Substance P,1-de-L-arginine-2-de-L-proline-3-de-L-lysine-4-D-alanine-
(2S)-N-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]-2-[[(2R)-2-aminopropanoyl]amino]pentanediamide | [Molecular Formula]
C44H65N11O10S | [MDL Number]
MFCD00076793 | [MOL File]
81381-50-2.mol | [Molecular Weight]
940.12 |
| Hazard Information | Back Directory | [Uses]
[DAla4] Substance P (4-11) is an analog of Substance P (Substance P (HY-P0201)) that inhibits the binding of 125I-Bolton Hunter-conjugated Eledoisin (Eledoisin (HY-P0006)) (IC50 of 0.5 μM) and 125I-Bolton Hunter-conjugated Substance P (IC50 of 0.15 μM) to rat brain cortex membranes[1]. | [References]
[1] M A Cascieri, et al. Demonstration of two distinct tachykinin receptors in rat brain cortex. J Biol Chem. 1985 Feb 10;260(3):1501-7. PMID:2578461 |
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