| Identification | Back Directory | [Name]
rac erythro-9-(2-Hydroxy-3-nonyl)adenine, Hydrochloride | [CAS]
81408-49-3 | [Synonyms]
EHNA monohydrochloride
(2R,3S)-EHNA hydrochloride | [Molecular Formula]
C14H24ClN5O | [MDL Number]
MFCD00151066 | [MOL File]
81408-49-3.mol | [Molecular Weight]
313.826 |
| Chemical Properties | Back Directory | [Melting point ]
163-170°C | [storage temp. ]
Hygroscopic, -20°C Freezer, Under Inert Atmosphere | [solubility ]
Soluble in DMSO > 10 mM | [form ]
Powder |
| Hazard Information | Back Directory | [Chemical Properties]
White to Off-White Solid | [Uses]
A potent inhibitor of phosphodiesterase II (PDE II) (IC50=800nM). Does ot inhibit other PDE isozymes (IC50>100uM). Inhibits the retrograde transport motor, dynein. Also inhibits adenosine deaminase (Ki=4nM). | [Definition]
ChEBI: A hydrochloride salt obtained by reaction of (2R,3S)-EHNA with one equivalent of hydrochloric acid. Selective inhibitor of cGMP-stimulated phosphodiesterase (PDE2) (IC50 = 0.8 - 4
M). Also a potent inhibitor of adenosine deaminase. | [storage]
Store at -20°C |
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