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81517-87-5

81517-87-5 Structure

81517-87-5 Structure
IdentificationBack Directory
[Name]

5-hydroxyeicosatetraenoic acid lactone
[CAS]

81517-87-5
[Synonyms]

5-hydroxyeicosatetraenoic acid lactone
6-[(1E,3Z,6Z,9Z)-pentadeca-1,3,6,9-tetraenyl]oxan-2-one
2H-Pyran-2-one, tetrahydro-6-(1E,3Z,6Z,9Z)-1,3,6,9-pentadecatetraen-1-yl-
[Molecular Formula]

C20H30O2
[MOL File]

81517-87-5.mol
[Molecular Weight]

302.45
Chemical PropertiesBack Directory
[Boiling point ]

445.7±34.0 °C(Predicted)
[density ]

0.979±0.06 g/cm3(Predicted)
[form ]

Clear to light-yellow liquid.
Hazard InformationBack Directory
[Uses]

(±)5-HETE lactone is the racemate of 5-HETE lactone. 5-HETE lactone is a metabolite generated by a series of enzymatic reactions of arachidonic acid, and is also a substrate of paraoxonase-1 (PON1). 5-HETE lactone can be used in the study of B cell activation[1][2].
[References]

[1] Tao C, et al. Reactivity of tricarbonyl (pentadienyl) iron (1+) cations: enantioselective synthesis of 5-HETE methyl ester[J]. The Journal of Organic Chemistry, 1993, 58(8): 2134-2143.
[2] Picardo C M. The hydrolysis of 5-HETE lactone by paraoxonase 1 and its stability in serum[M]. 2007.
81517-87-5 suppliers list
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