| Identification | Back Directory | [Name]
FLUPROPADINE | [CAS]
81613-59-4 | [Synonyms]
1-[3-[3,5-bis(trifluoromethyl)phenyl]prop-2-ynyl]-4-tert-butyl-piperid ine
Piperidine, 1-[3-[3,5-bis(trifluoromethyl)phenyl]-2-propyn-1-yl]-4-(1,1-dimethylethyl)- | [Molecular Formula]
C20H23F6N | [MOL File]
81613-59-4.mol | [Molecular Weight]
391.39 |
| Hazard Information | Back Directory | [Production Methods]
The industrial scale manufacturing of flupropadine is not described in open literature, but its structure and the limited synthetic information available indicate that commercial production followed a straightforward modular assembly of three components: (1) synthesis of the tert butylpiperidine ring, (2) preparation of the bis(trifluoromethyl)phenyl substituted propargyl intermediate, and (3) N alkylation of the piperidine with the propargyl side chain to form the final tertiary amine. A key step involved coupling the substituted propargyl fragment with the tert butylpiperidine core, consistent with standard late 20th century amine alkylation processes used for lipophilic rodenticides. | [Mechanism of action]
Chronic, cumulative anticoagulant | [Pesticide Type]
Rodenticide |
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