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816432-15-2

816432-15-2 Structure

816432-15-2 Structure
IdentificationBack Directory
[Name]

CEP dipeptide 1
[CAS]

816432-15-2
[Synonyms]

CS-2090
CEP dipeptide 1
CEP dipeptide 1, >98%
L-Norleucine, N-acetylglycyl-6-[2-(2-carboxyethyl)-1H-pyrrol-1-yl]-, 21-methyl ester
[Molecular Formula]

C18H27N3O6
[MDL Number]

MFCD29472223
[MOL File]

816432-15-2.mol
[Molecular Weight]

381.42
Chemical PropertiesBack Directory
[Boiling point ]

670.8±55.0 °C(Predicted)
[density ]

1.24±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

4.74±0.10(Predicted)
[color ]

Off-white to yellow
Hazard InformationBack Directory
[Uses]

CEP dipeptide 1 is a CEP dipeptide with potent angiogenic activity; mediators of age-related macular degeneration (AMD).
[References]

[1] Lu L, et al. Synthesis and structural characterization of carboxyethylpyrrole-modified proteins: mediators of age-related macular degeneration. Bioorg Med Chem. 2009 Nov 1;17(21):7548-61. DOI:10.1016/j.bmc.2009.09.009
[2] Wang H, et al. 4-Hydroxy-7-oxo-5-heptenoic Acid (HOHA) Lactone is a Biologically Active Precursor for the Generation of 2-(ω-Carboxyethyl)pyrrole (CEP) Derivatives of Proteins and Ethanolamine Phospholipids. Chem Res Toxicol. 2015 May 18;28(5):967-77. DOI:10.1021/acs.chemrestox.5b00001
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