| Identification | Back Directory | [Name]
1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, α-(2-carboxyethyl)-, 1,4,7,10-tetrakis(1,1-dimethylethyl) ester, (αR)- | [CAS]
817562-90-6 | [Synonyms]
(R)-tert-Bu4-DOTAGA
(R)-DOTAGA-(COOt-Bu)4
2-(R)-2-(4,7,10-tris-tert-butoxycarbonylmethyl-1,4,7,10-tetraazacyclododec-1-yl)-pentanedioic acid, 1-tert-butyl ester
(R)-5-(tert-Butoxy)-5-oxo-4-(4,7,10-tris(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)pentanoic acid
(αR)-α-(2-carboxyethyl)-1,4,7,10-tetrakis(1,1-dimethylethyl) ester-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic
(αR)- 1,4,7,10-tetrakis(1,1-dimethylethyl) ester α-(2-carboxyethyl)-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid
1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, a-(2-carboxyethyl)-, 1,4,7,10-tetrakis(1,1-dimethylethyl) ester, (aR)-
1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, α-(2-carboxyethyl)-, 1,4,7,10-tetrakis(1,1-dimethylethyl) ester, (αR)- | [Molecular Formula]
C35H64N4O10 | [MDL Number]
MFCD30347823 | [MOL File]
817562-90-6.mol | [Molecular Weight]
700.9 |
| Chemical Properties | Back Directory | [Boiling point ]
710.3±60.0 °C(Predicted) | [density ]
1.081±0.06 g/cm3(Predicted) | [storage temp. ]
Storage temp. 2-8°C | [pka]
4.52±0.10(Predicted) | [Appearance]
White to off-white Solid |
| Hazard Information | Back Directory | [Uses]
Cyclen derivative (R)-tert-Bu4-DOTAGA, a key intermediate for the manufacture of a magnetic resonance imaging (MRI) candidate.
| [References]
[1] Levy, S. G., Jacques*, V., Zhou, K. L., Kalogeropoulos, S., Schumacher, K., Amedio, J. C., Scherer, J. E., Witowski, S. R., Lombardy, R., & Koppetsch, K. (2009). Development of a Multigram Asymmetric Synthesis of 2-(R)-2-(4,7,10-Tris tert-Butylcarboxymethyl-1,4,7,10-tetraazacyclododec-1-yl)-pentanedioic Acid, 1-tert-Butyl Ester, (R)-tert-Bu4-DOTAGA(1). Organic Process Research & Development, 13 3, 535–542. https://doi.org/10.1021/op8002932
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| Spectrum Detail | Back Directory | [Spectrum Detail]
1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, α-(2-carboxyethyl)-, 1,4,7,10-tetrakis(1,1-dimethylethyl) ester, (αR)-(817562-90-6)1HNMR
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