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819868-62-7

819868-62-7 Structure

819868-62-7 Structure
IdentificationBack Directory
[Name]

2H-1-Benzopyran-2-carboxamide, 3,4-dihydro-6-hydroxy-7-methoxy-N-phenyl-
[CAS]

819868-62-7
[Synonyms]

KL1156
KL-1156
KL 1156
2H-1-Benzopyran-2-carboxamide, 3,4-dihydro-6-hydroxy-7-methoxy-N-phenyl-
[Molecular Formula]

C17H17NO4
[MOL File]

819868-62-7.mol
[Molecular Weight]

299.32
Chemical PropertiesBack Directory
[Boiling point ]

568.5±50.0 °C(Predicted)
[density ]

1.310±0.06 g/cm3(Predicted)
[pka]

10.48±0.40(Predicted)
Hazard InformationBack Directory
[Description]

KL-1156 is a NF-κB inhibitor and lipopolysaccharide (LPS)-induced nitric oxide production inhibitor.
[Uses]

BMS-358233 (compound 3) is a Lck inhibitor (IC50: 1 nM; Ki: 540 pM) and inhibits T cell proliferation (IC50: 262 nM).
[References]

[1] Inhibitory mechanism of chroman compound on LPS-induced nitric oxide production and nuclear factor-jB activation
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