| Identification | Back Directory | [Name]
Flerobuterol | [CAS]
82101-08-4 | [Synonyms]
CRL40996
CRL-40996
CRL-40827
CRL 40996
Flerobuterol HCl
Flerobuterol hydrochloride | [Molecular Formula]
C12H19ClFNO | [MOL File]
82101-08-4.mol | [Molecular Weight]
247.737 |
| Hazard Information | Back Directory | [Description]
Flerobuterol, also known as CRL-40996, is a β adrenergic receptor agonist potentially for the treatment of major depressive disorder. Flerobuterol enhances serotonergic neurotransmission: an electrophysiological study in the rat brain. Flerobuterol, similar to other beta-adrenergic agonists, acutely increases 5-HT synthesis, in part, through an elevation of brain Trp availability. | [Uses]
Flerobuterol hydrochloride is a beta-adrenoceptor agonist with antidepressant activity. Flerobuterol hydrochloride enhances serotonergic neurotransmission[1]. | [References]
[1] Bouthillier A, et al. Flerobuterol, a beta-adrenoceptor agonist, enhances serotonergic neurotransmission: an electrophysiological study in the rat brain. Psychopharmacology (Berl). 1991;103(3):357-65. DOI:10.1007/BF02244290 |
|
|