| | Identification | Back Directory |  | [Name] 
 humantenirine
 |  | [CAS] 
 82375-30-2
 |  | [Synonyms] 
 humantenirine
 Humanlenirine
 4-Demethyl-11-methoxyhumantenine
 Spiro[3H-indole-3,8'(7'H)-[4,7]methanooxepino[4,3-b]pyridin]-2(1H)-one, 3'-ethylidene-1',2',3',4',4'a,5',9',9'a-octahydro-1,6-dimethoxy-, (3S,3'Z,4'R,4'aS,7'R,9'aS)-
 |  | [Molecular Formula] 
 C21H26N2O4
 |  | [MDL Number] 
 MFCD26406082
 |  | [MOL File] 
 82375-30-2.mol
 |  | [Molecular Weight] 
 370.44
 | 
 | Hazard Information | Back Directory |  | [Description] 
 Humantenirine is an oxindole alkaloid that has been shown to have potent inhibition of the enzyme activities. It is a natural product that has been isolated from the plant Humantenia nitens, which is found in Gabon, Africa. Humantenirine has a skeleton similar to other indole alkaloids and contains a hydroxy group on one of the rings. This compound has been shown to be stereoselective and monoterpenoid and may have potential as an anti-inflammatory drug.
 |  | [Chemical Properties] 
 Humantenirine ( C21H26N2O4 colorless cubic crystals, mp 168- 169°C, M+ 370.1944). Its UV spectrum is similar to that of gelsemicine; hence both have the same chromophore, 7-methoxy-3,3-disubstituted N-methoxy-oxindole.
 |  | [Occurrence] 
 Humantenirine is a natural product found in Gelsemium sempervirens, Gelsemium elegans, and Gelsemium rankinii with data available.
 |  | [target] 
 P450 (e.g. CYP17)
 | 
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