| Identification | Back Directory | [Name]
JNJ 20788560 | [CAS]
825649-28-3 | [Synonyms]
JNJ 20788560
JNJ 20788560,JNJ20788560
JNJ-20788560, 10 mM in DMSO
9-(8-azabicyclo[3.2.1]octan-3-ylidene)-N,N-diethylxanthene-3-carboxamide
9H-Xanthene-3-carboxamide, 9-(8-azabicyclo[3.2.1]oct-3-ylidene)-N,N-diethyl-
9-(8-azabicyclo[3.2.1]octan-3-ylidene)-N,N-diethyl-9H-xanthene-3-carboxamide | [Molecular Formula]
C25H28N2O2 | [MDL Number]
MFCD17167086 | [MOL File]
825649-28-3.mol | [Molecular Weight]
388.5 |
| Chemical Properties | Back Directory | [Boiling point ]
567.8±50.0 °C(Predicted) | [density ]
1.186±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
10.58±0.20(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
JNJ-20788560 is a selective and orally active delta opioid receptor agonist with an affinity of 2.0 nM for DOR (rat brain cortex binding assay). JNJ-20788560 also is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic tolerance, or physical dependence. JNJ-20788560 can be used for the research of the relief of inflammatory hyperalgesia[1]. | [References]
[1] Codd EE, et al. JNJ-20788560 [9-(8-azabicyclo[3.2.1]oct-3-ylidene)-9H-xanthene-3-carboxylic acid diethylamide], a selective delta opioid receptor agonist, is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic tolerance, or physical dependence. J Pharmacol Exp Ther. 2009 Apr;329(1):241-51. DOI:10.1124/jpet.108.146969 |
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