| Identification | Back Directory | [Name]
diazoketone methotrexate | [CAS]
82972-54-1 | [Synonyms]
diazoketone methotrexate
Methotrexate diazoketone analog | [Molecular Formula]
C21H22N10O4 | [MOL File]
82972-54-1.mol | [Molecular Weight]
478.464 |
| Hazard Information | Back Directory | [Description]
Diazoketone methotrexate is an analogs of methotrexate, and a potential antitumor agent. | [Uses]
Diazoketone methotrexate, an analog of methotrexate, is an antitumor agent. Diazoketone methotrexate inhibits cell growth and inhibits synthesis of thymidylate[1]. | [References]
[1] Gangjee A, et al. Diazoketone and chloromethylketone analogs of methotrexate as potential antitumor agents. J Pharm Sci. 1982 Jun;71(6):717-9. DOI:10.1002/jps.2600710631 |
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