| Identification | Back Directory | [Name]
PLATELET FACTOR 4 (58-70) (HUMAN) | [CAS]
82989-21-7 | [Synonyms]
PF4 (58-70) (HUMAN)
PLATELET FACTOR-4 (HUMAN, 58-70)
PLATELET FACTOR 4 (58-70) (HUMAN)
platelet factor 4 fragment 58-70 human
PLATELET FACTOR 4 (58-70) (HUMAN) USP/EP/BP
PRO-LEU-TYR-LYS-LYS-ILE-ILE-LYS-LYS-LEU-LEU-GLU-SER
H-PRO-LEU-TYR-LYS-LYS-ILE-ILE-LYS-LYS-LEU-LEU-GLU-SER-OH
L-Prolyl-L-leucyl-L-tyrosyl-L-lysyl-L-lysyl-L-isoleucyl-L-isoleucyl-L-lysyl-L-lysyl-L-leucyl-L-leucyl-L-α-glutamyl-L-serine | [Molecular Formula]
C76H133N17O18 | [MDL Number]
MFCD00237228 | [MOL File]
82989-21-7.mol | [Molecular Weight]
1572.97 |
| Chemical Properties | Back Directory | [Boiling point ]
1739.7±65.0 °C(Predicted) | [density ]
1?+-.0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [form ]
Solid | [pka]
2.95±0.10(Predicted) | [color ]
White to off-white | [Sequence]
Pro-Leu-Tyr-Lys-Lys-Ile-Ile-Lys-Lys-Leu-Leu-Glu-Ser |
| Hazard Information | Back Directory | [Uses]
Platelet Factor 4 (58-70), human, a peptide based on the amino acid sequence corresponding to residues 58-70 of platelet factor-4 (PF-4), contains the major heparin-binding domain, which is not sufficient for full antiangiogenic activity[1]. | [References]
[1] Jouan V, et al. Inhibition of in vitro angiogenesis by platelet factor-4-derived peptides and mechanism of action. Blood. 1999 Aug 1;94(3):984-93. PMID:10419890 |
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