| Identification | Back Directory | [Name]
11beta,13-Dihydrolactucin | [CAS]
83117-63-9 | [Synonyms]
11β,13-Dihydrolactucin
11β,13-Dihydrolactucin
11beta,13-Dihydrolactucin
Azuleno[4,5-b]furan-2,7-dione, 3,3a,4,5,9a,9b-hexahydro-4-hydroxy-9-(hydroxymethyl)-3,6-dimethyl-, (3S,3aR,4S,9aS,9bR)- | [Molecular Formula]
C15H18O5 | [MDL Number]
MFCD24849264 | [MOL File]
83117-63-9.mol | [Molecular Weight]
278.3 |
| Chemical Properties | Back Directory | [Melting point ]
91 °C(Solv: methanol (67-56-1)) | [Boiling point ]
548.0±50.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3(Predicted) | [pka]
13.68±0.70(Predicted) | [LogP]
0.380 (est) |
| Hazard Information | Back Directory | [Uses]
11β,13-Dihydrolactucin is an antimicrobial agent. 11β,13-Dihydrolactucin also has several biological properties, including antioxidant, anti-inflammatory, and antitumor activities[1]. | [Definition]
ChEBI: 11beta,13-dihydrolactucin is a sesquiterpene lactone obtained by formal hydrogenation across the 11,13-double bond of lactucin. Found in chicory It has a role as a plant metabolite. It is an azulenofuran, a cyclic terpene ketone, an enone, a secondary alcohol, a sesquiterpene lactone and a primary alcohol. It is functionally related to a lactucin. | [References]
[1] Weng H, et al. Low Oral Bioavailability and Partial Gut Microbiotic and Phase II Metabolism of Brussels/Witloof Chicory Sesquiterpene Lactones in Healthy Humans. Nutrients. 2020 Nov 28;12(12):3675. DOI:10.3390/nu12123675 |
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