| Identification | Back Directory | [Name]
methylnaltrexone | [CAS]
83387-25-1 | [Synonyms]
Mrz 2663
Mrz-2663
Naltrexone mb
methylnaltrexone
Methylnaltrexonium
N-Methylnaltrexone
3-O-Methylnaltrexone
Naltrexone methyl ether
17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinanium-6-one
17-(Cyclopropylmethyl)-4,5α-epoxy-3-methoxy-14-hydroxymorphinan-6-one
3-Methoxy-14-hydroxy-17-(cyclopropylmethyl)-4,5α-epoxymorphinan-6-one
4,5α-Epoxy-3-methoxy-14β-hydroxy-17-(cyclopropylmethyl)morphinan-6-one
17-(Cyclopropylmethyl)-4,5alpha-epoxy-3,14-dihydroxy-17-methyl-6-oxomorphinanium
Morphinanium, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-17-methyl-6-oxo-, (5alpha)- | [Molecular Formula]
C21H26NO4+ | [MOL File]
83387-25-1.mol | [Molecular Weight]
356.435 |
| Hazard Information | Back Directory | [Definition]
ChEBI: Methylnaltrexone is a member of phenanthrenes. | [General Description]
Methylnaltrexone (Relistor) is the methylated, quaternaryform of naltrexone . The permanently chargednitrogen prevents the drug from crossing the blood-brainbarrier. Thus, it only acts as an antagonist at peripheralopioid receptors. Relistor was approved in April 2008 totreat opioid-induced constipation in patients receiving palliativecare. It is administered as a SC injection once everyother day. |
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