| Identification | Back Directory | [Name]
((2R,4S,5R)-4-(tert-butyldiphenylsilyloxy)-5-(hydroxyMethyl)-tetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione | [CAS]
83467-48-5 | [Synonyms]
3'-O-(t-Butyldiphenylsilyl)thymidine
3’-O-tert-Butyldiphenylsilylthymidine
2'-Deoxy-3'-O-[(2-methyl-2-propanyl)(diphenyl)silyl]-3,4-dihydrot hymidine
3-[(2R,4S,5R)-4-[tert-butyl(diphenyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione
((2R,4S,5R)-4-(tert-butyldiphenylsilyloxy)-5-(hydroxyMethyl)-tetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione | [Molecular Formula]
C26H32N2O5Si | [MDL Number]
MFCD16038960 | [MOL File]
83467-48-5.mol | [Molecular Weight]
480.63 |
| Hazard Information | Back Directory | [Uses]
3’-O-(t-Butyldiphenylsilyl) thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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