ChemicalBook--->CAS DataBase List--->83546-42-3

83546-42-3

83546-42-3 Structure

83546-42-3 Structure
IdentificationBack Directory
[Name]

2'-Fluoro-5-ethylarabinosyluracil
[CAS]

83546-42-3
[Synonyms]

2'-Fluoro-5-ethylarabinosyluracil
2'-Deoxy-2'-fluoro-5-ethyl-arabinouridine
2’-Deoxy-2’-fluoro-5-ethyl-arabinouridine
2'-Fluoro-5-ethyl-beta-D-arabinofuranosyluracil
5-Ethyl-2'-deoxy-2'-fluoro-beta-D-arabinouridine
1-(2-deoxy-2-fluoroarabinofuranosyl)-5-ethyluracil
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-
5-Ethyl-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
5-Ethyl-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
[Molecular Formula]

C11H15FN2O5
[MDL Number]

MFCD11973639
[MOL File]

83546-42-3.mol
[Molecular Weight]

274.25
Chemical PropertiesBack Directory
[density ]

1.497±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[pka]

9.610±0.10(predicted)
Hazard InformationBack Directory
[Uses]

1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].
[References]

[1] Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93. DOI:10.3390/molecules16097980
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