| Identification | Back Directory | [Name]
L-Phenylalanine, L-alanyl-L-valyl-L-threonyl-L-α-aspartyl-L-histidyl-L-prolyl-L-α-aspartyl-L-arginyl-L-leucyl-L-tryptophyl-L-alanyl-L-tryptophyl-L-α-glutamyl-L-lysyl- | [CAS]
835655-37-3 | [Synonyms]
L-Phenylalanine, L-alanyl-L-valyl-L-threonyl-L-α-aspartyl-L-histidyl-L-prolyl-L-α-aspartyl-L-arginyl-L-leucyl-L-tryptophyl-L-alanyl-L-tryptophyl-L-α-glutamyl-L-lysyl- | [Molecular Formula]
C88H123N23O23 | [MOL File]
835655-37-3.mol | [Molecular Weight]
1871.06 |
| Hazard Information | Back Directory | [Uses]
TCL1(10-24) is a encompassing the betaA strand of human TCL1. TCL1(10-24) is a Akt inhibitor. TCL1(10-24) interacts with the Akt PH domain prevented phosphoinositide binding and hence inhibits membrane translocation and activation of Akt. TCL1(10-24) inhibits cellular proliferation and anti-apoptosis. TCL1(10-24) has tumor growth in vivo[1]. | [References]
[1] Makoto Hiromura, et al. Inhibition of Akt kinase activity by a peptide spanning the betaA strand of the proto-oncogene TCL1. J Biol Chem. 2004 Dec 17;279(51):53407-18. DOI:10.1074/jbc.M403775200 |
|
| Company Name: |
Fuan Bio
|
| Tel: |
15002819872 |
| Website: |
fuanbio.com |
|