ChemicalBook--->CAS DataBase List--->83603-31-0

83603-31-0

83603-31-0 Structure

83603-31-0 Structure
IdentificationBack Directory
[Name]

15(R)-HETE
[CAS]

83603-31-0
[Synonyms]

15(R)-HETE
JSFATNQSLKRBCI-UDQWCNDOSA-N
15R-HYDROXY-5Z,8Z,11Z,13E-EICOSATETRAENOIC ACID
5,8,11,13-Eicosatetraenoic acid, 15-hydroxy-, (5Z,8Z,11Z,13E,15R)-
[Molecular Formula]

C20H32O3
[MDL Number]

MFCD00221507
[MOL File]

83603-31-0.mol
[Molecular Weight]

320.47
Chemical PropertiesBack Directory
[solubility ]

0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
[form ]

Liquid
[color ]

Colorless to light yellow
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)
GHS02
[Signal word ]

Danger
Hazard InformationBack Directory
[Description]

15(R)-HEDE is isolated by the chromatographic resolution of (±)15-HEDE. There are no reports of biological activity associated with 15(R)-HEDE in the literature.
[Uses]

15(R)-HETE is an isomer of 15-HETE. 15-HETE is a lipid mediator derived from arachidonic acid and can be used for the study of asthma[1].
[References]

[1] Johnsson AK, et al. COX-1 dependent biosynthesis of 15-hydroxyeicosatetraenoic acid in human mast cells. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 May;1866(5):158886. DOI:10.1016/j.bbalip.2021.158886
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