| Identification | Back Directory | [Name]
1,4-DIACETOXY-2,3-DICYANOBENZENE | [CAS]
83619-73-2 | [Synonyms]
ADB
3,6-DIACETOXYPHTHALONITRILE
VXDCGBVAZDYTFK-UHFFFAOYSA-N
1,4-DIACETOXY-2,3-DICYANOBENZENE
2,3-DICYANO-1,4-HYDROQUINONE DIACETATE
1,4-DIACETOXY-2,3-DICYANOBENZENE, FOR FL UORESCENCE
1,4-Diacetoxy-2,3-dicyanobenzene, 2,3-Dicyano-1,4-hydroquinone diacetate, ADB | [Molecular Formula]
C12H8N2O4 | [MDL Number]
MFCD00036857 | [MOL File]
83619-73-2.mol | [Molecular Weight]
244.2 |
| Chemical Properties | Back Directory | [Melting point ]
166-167 °C(lit.) | [Boiling point ]
447.5±45.0 °C(Predicted) | [density ]
1.34±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
DMSO: soluble | [form ]
A crystalline solid | [Appearance]
Solid Powder |
| Hazard Information | Back Directory | [Description]
3,6-diacetoxy Phthalonitrile is a cell-permeable fluorescent probe for measuring intracellular pH by flow cytometry in living cells. It s cleaved by cytosolic esterases to form the fluorescent pH indicator 2,3-dicyano-hydroquinone (DCH), which is excited at UV wavelengths. | [Uses]
3,6-Diacetoxyphthalonitrile is a fluorescent probe for monitoring intracellular pH by flow cytometry in living cells. It rapidly crosses cell membranes and is cleaved by cytosolic esterases to form the fluorescent pH indicator 2,3-dicyano-hydroquinone, which is excited at UV wavelengths. | [storage]
Store at -20°C | [Excitation / Emission Maximum]
351 nm/450-476 nm (pH 5.0-10.0) |
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