| Identification | Back Directory | [Name]
VINCLOZOLIN | [CAS]
83792-61-4 | [Synonyms]
M2
VORLAN
RONILAN
FLOTILLA
RONILAN(R)
VINCLOZOLIN
Vinclozolin M2
N-(3,5-dichlorophenyl)-2-hydroxy-2-methylbut-3-enamide
N-(3,5-Dichlorophenyl)-2-hydroxy-2-methyl-3-butenamide
3-Butenamide, N-(3,5-dichlorophenyl)-2-hydroxy-2-methyl-
3-(3,5-DICHLOROPHENYL)-5-METHYL-5-VINYLOXAZOLIDINE-2,4-DIONE
3-(3,5-DICHLOROPHENYL)-5-ETHENYL-5-METHYL-2,4-OXAZOLIDINEDIONE | [Molecular Formula]
C11H11Cl2NO2 | [MDL Number]
MFCD00055511 | [MOL File]
83792-61-4.mol | [Molecular Weight]
260.12 |
| Questions And Answer | Back Directory | [?Properties]
Molecular formula C12H9Cl2NO3, Mr. 286.Soluble in acetone, benzene, chloroform, and ethyl acetate. | [Biological functions]
Vinclozolin inhibits androgen-induced gene expression in vivo.Vinclozolin treatment reduces androgen-dependent organ weights in adult rats and the anogenital distance of male pups at birth, by in utero exposure.Embryonic exposure to vinclozolin also modifies the developing testis and prostate transcriptome, including DNA methyltransferases.The metabolites of vinclozolin (M1 and M2) block AR binding to the androgen response element (ARE) and inhibit dihydrotestosterone (DHT)-induced transcriptional activation. |
| Chemical Properties | Back Directory | [Boiling point ]
426.9±45.0 °C(Predicted) | [density ]
1.379±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2)(1:1): .5 mg/ml | [form ]
A crystalline solid | [pka]
12.39±0.29(Predicted) |
| Hazard Information | Back Directory | [Description]
Vinclozolin is a dicarboximide fungicide, and an antiandrogen. | [Uses]
Vinclozolin M2 is a dicarboximide fungicide. | [Definition]
ChEBI: M2 is an anilide. | [storage]
Store at -20°C |
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