| Identification | Back Directory | [Name]
SCH 32615 | [CAS]
83861-02-3 | [Synonyms]
SCH 32615
N-[N-[(S)-1-Carboxy-2-phenylethyl]-L-phenylalanyl]-β-alanine | [Molecular Formula]
C21H24N2O5 | [MDL Number]
MFCD00899084 | [MOL File]
83861-02-3.mol | [Molecular Weight]
384.426 |
| Hazard Information | Back Directory | [Uses]
SCH 32615 is an enkephalinase (the enzymes responsible for the degradation of endogenous enkephalins) inhibitor. SCH 32615 can enhance surgery- and pregnancy-induced analgesia in mice[1][2]. | [in vivo]
SCH 32615 (150 mg/kg; s.c.) enhances surgery activated endogenous analgesia in mice[1]. | [References]
[1] Jayaram A, et, al. An enkephalinase inhibitor, SCH 32615, augments analgesia induced by surgery in mice. Anesthesiology. 1995 May;82(5):1283-7. DOI:10.1097/00000542-199505000-00024
[2] Jayaram A, et, al. SCH 32615, an enkephalinase inhibitor, enhances pregnancy-induced analgesia in mice. Anesth Analg. 1995 May;80(5):944-8. DOI:10.1097/00000539-199505000-00015
[3] Chipkin RE, et, al. Pharmacology of SCH 34826, an orally active enkephalinase inhibitor analgesic. J Pharmacol Exp Ther. 1988 Jun;245(3):829-38. PMID:3164388 |
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| Company Name: |
InvivoChem
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13549236410 |
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https://www.invivochem.cn/ |
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