| Identification | Back Directory | [Name]
（2E，6Z，8E，10E）-N-(2-hydroxy-2-methylpropyl)dodeca-2,6,8,10-tetraenamide | [CAS]
83883-10-7 | [Synonyms]
(2E,6Z,8E,10E)
Hydroxy-α-sanshool
alpha-Hydroxy-Sanshool
Hydroxy-alpha-Sanshool
dodeca-2,6,8,10-tetraenamide
-N-(2-Hydroxy-2-methylpropyl)
(2E,6Z,8E,10E)-N-(2-hydroxy-2-Methylpropyl)dodeca-2,6,8,10-tetra
（2E，6Z，8E，10E）-N-(2-hydroxy-2-methylpropyl)dodeca-2,6,8,10-tetraenamide
2,6,8,10-Dodecatetraenamide, N-(2-hydroxy-2-methylpropyl)-, (2E,6Z,8E,10E)- | [Molecular Formula]
C16H25NO2 | [MDL Number]
MFCD17779317 | [MOL File]
83883-10-7.mol | [Molecular Weight]
263.38 |
| Chemical Properties | Back Directory | [Boiling point ]
471.5±45.0 °C(Predicted) | [density ]
0.973±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Viscous Liquid | [pka]
14.59±0.29(Predicted) | [color ]
White to yellow | [InChI]
InChI=1S/C16H25NO2/c1-4-5-6-7-8-9-10-11-12-13-15(18)17-14-16(2,3)19/h4-9,12-13,19H,10-11,14H2,1-3H3,(H,17,18)/b5-4+,7-6+,9-8-,13-12+ | [InChIKey]
LHFKHAVGGJJQFF-UEOYEZOQSA-N | [SMILES]
C(NCC(O)(C)C)(=O)/C=C/CC/C=C\C=C\C=C\C |
| Hazard Information | Back Directory | [Chemical Properties]
Derived from prickly ash. | [Definition]
ChEBI: Hydroxy-alpha-sanshool is a fatty amide. | [Biological Activity]
Hydroxy-?α-?sanshool, an alkylamide isolated from piperine, is a covalent agonist of TRPA1 and a non-covalent agonist of TRPV1 with EC50 values ??of 69 and 1.1 μM, respectively. | [Synthesis]
（2E，6Z，8E，10E）-N-(2-hydroxy-2-methylpropyl)dodeca-2,6,8,10-tetraenamide can be prepared by the reaction of 2E,6Z,8E,10E-dodecatetraenoic acid and 1-amino-2-methyl-2-propanol in the presence of HBTU and triethylamine. | [target]
| Human Endogenous Metabolite < span> | |
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