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84138-86-3

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84138-86-3 Structure

84138-86-3 Structure
IdentificationBack Directory
[Name]

N6-BENZOYL-5'-O-(DIMETHOXYTRITYL)-3'-DEOXYADENOSINE
[CAS]

84138-86-3
[Synonyms]

N6-Benzoyl-3'-deoxy-5'-O-DMT-adenosine
N6-Benzoyl-5'-O-(dimethoxytrityl)-3'-deoxyadenosine
N6-Benzoyl-5’-O-(4,4-dimethoxytrityl)-3’-deoxy adenosine
N6-Benzoyl-5'-O-(4,4-dimethoxytrityl)-3'-deoxy adenosine
N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-deoxyadenosine
Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-
N-(9-((2R,3R,5S)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-hydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
[Molecular Formula]

C38H35N5O6
[MDL Number]

MFCD01630966
[MOL File]

84138-86-3.mol
[Molecular Weight]

657.71
Chemical PropertiesBack Directory
[density ]

1.32±0.1 g/cm3(Predicted)
[pka]

7.87±0.43(Predicted)
Hazard InformationBack Directory
[Uses]

N-Benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-3′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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