Identification | Back Directory | [Name]
2-Propenamide, N-(1-ethylpropyl)-3-(4-methoxyphenyl)-, (2E)- | [CAS]
844900-50-1 | [Synonyms]
TMPPAA 2-Propenamide, N-(1-ethylpropyl)-3-(4-methoxyphenyl)-, (2E)- | [Molecular Formula]
C15H21NO2 | [MDL Number]
MFCD03638097 | [MOL File]
844900-50-1.mol | [Molecular Weight]
247.33 |
Hazard Information | Back Directory | [Description]
TMPPAA is an allosteric agonist and positive allosteric modulator (PAM) of 5-HT3 receptor. | [Uses]
TMPPAA is an allosteric agonist and positive allosteric modulator of the 5-HT3 receptor. TMPPAA enhances 5-HT-mediated 5-HT3AR signaling[1]. | [References]
[1] Gasiorek A, et al. Delineation of the functional properties and the mechanism of action of TMPPAA, an allosteric agonist and positive allosteric modulator of 5-HT3 receptors. Biochem Pharmacol. 2016 Jun 15;110-111:92-108. DOI:10.1016/j.bcp.2016.04.004 |
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