ChemicalBook--->CAS DataBase List--->844900-50-1

844900-50-1

844900-50-1 Structure

844900-50-1 Structure
IdentificationBack Directory
[Name]

2-Propenamide, N-(1-ethylpropyl)-3-(4-methoxyphenyl)-, (2E)-
[CAS]

844900-50-1
[Synonyms]

TMPPAA
2-Propenamide, N-(1-ethylpropyl)-3-(4-methoxyphenyl)-, (2E)-
[Molecular Formula]

C15H21NO2
[MDL Number]

MFCD03638097
[MOL File]

844900-50-1.mol
[Molecular Weight]

247.33
Hazard InformationBack Directory
[Description]

TMPPAA is an allosteric agonist and positive allosteric modulator (PAM) of 5-HT3 receptor.
[Uses]

TMPPAA is an allosteric agonist and positive allosteric modulator of the 5-HT3 receptor. TMPPAA enhances 5-HT-mediated 5-HT3AR signaling[1].
[References]

[1] Gasiorek A, et al. Delineation of the functional properties and the mechanism of action of TMPPAA, an allosteric agonist and positive allosteric modulator of 5-HT3 receptors. Biochem Pharmacol. 2016 Jun 15;110-111:92-108. DOI:10.1016/j.bcp.2016.04.004
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