| Identification | Back Directory | [Name]
Isoastragaloside I | [CAS]
84676-88-0 | [Synonyms]
Isoastragaloside I
Isoastragaloside I, BR
Isoastragaloside I USP/EP/BP
Isoastragaloside I (Isoastragaloside-I)
β-D-Glucopyranoside, (3β,6α,16β,20R,24S)-3-[(2,4-di-O-acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl
(3beta,6alpha,16beta,20R,24S)-3-[(2,4-Di-O-acetyl-beta-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl beta-D-glucopyranoside | [Molecular Formula]
C45H72O16 | [MDL Number]
MFCD17214429 | [MOL File]
84676-88-0.mol | [Molecular Weight]
869.04 |
| Chemical Properties | Back Directory | [Boiling point ]
920.6±65.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
Acetonitrile: Soluble
DMSO: Soluble | [form ]
Solid | [pka]
12.61±0.70(Predicted) | [color ]
White to light brown |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Astragalus membranaceus (Fisch.) Bunge. | [Uses]
Isoastragaloside I has the functions of relieving cough and expectorating phlegm, digesting food and dissipating stagnation, promoting blood circulation and dissipating blood stasis. | [Biological Activity]
Isoastragaloside I (Isoastragaloside I) is a natural compound of traditional Chinese medicine Astragalus, which has the activity of increasing the amount of adiponectin. | [References]
[1] HONGSHUAI LIU. Isoastragaloside I inhibits NF-κB activation and inflammatory responses in BV-2 microglial cells stimulated with lipopolysaccharide.[J]. International journal of molecular medicine, 2017: 1270-1276. DOI: 10.3892/ijmm.2017.3114
[2] AIMIN XU. Selective elevation of adiponectin production by the natural compounds derived from a medicinal herb alleviates insulin resistance and glucose intolerance in obese mice.[J]. Endocrinology, 2009: 625-633. DOI: 10.1210/en.2008-0999
[3] WEN YU . A saponin from astragalus promotes pancreatic ductal organoids differentiation into insulin-producing cells[J]. Phytomedicine, 2022, 102: Article 154190. DOI: 10.1016/j.phymed.2022.154190 |
|
|