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849727-81-7

849727-81-7 Structure

849727-81-7 Structure
IdentificationBack Directory
[Name]

5-[3-[4-[2-(4-Fluorophenyl)ethoxy]phenyl]propyl]-2-furancarboxylic Acid
[CAS]

849727-81-7
[Synonyms]

AMPK Activator
MPLLLQUZNJSVTK-UHFFFAOYSA-N
5-[3-[4-[2-(4-Fluorophenyl)ethoxy]phenyl]propyl]-2-furancarboxylic Acid
2-Furancarboxylic acid, 5-[3-[4-[2-(4-fluorophenyl)ethoxy]phenyl]propyl]-
[Molecular Formula]

C22H21FO4
[MOL File]

849727-81-7.mol
[Molecular Weight]

368.4
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 25 mg/ml; Ethanol: 2 mg/ml
[form ]

A crystalline solid
[color ]

light yellow
[InChI]

1S/C22H21FO4/c23-18-8-4-17(5-9-18)14-15-26-19-10-6-16(7-11-19)2-1-3-20-12-13-21(27-20)22(24)25/h4-13H,1-3,14-15H2,(H,24,25)
[InChIKey]

MPLLLQUZNJSVTK-UHFFFAOYSA-N
[SMILES]

Fc1ccc(cc1)CCOc2ccc(cc2)CCCc3[o]c(cc3)C(=O)O
Safety DataBack Directory
[WGK Germany ]

WGK 1
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

5-[3-[4-[2-(4-Fluorophenyl)ethoxy]phenyl]propyl]-2-furancarboxylic Acid, is an indirect activator of AMP-activated protein kinase, which is an enzyme that plays a role in cellular energy homeostasis.
[Uses]

5-[3-[4-[2-(4-Fluorophenyl)ethoxy]phenyl]propyl]-2-furancarboxylic Acid, is an indirect activator of AMP-activated protein kinase, which is an enzyme that plays a role in cellular energy homeostasis.
[Biological Activity]

Cell permeable: yes''EC50 = 11.7 μM enhancing glucose uptake in L6 myocytes''Primary Target
AMPK''Product does not compete with ATP.''Reversible: no
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