| Chemical Properties | Back Directory | [density ]
1.12±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 2mg/mL, clear | [form ]
powder | [pka]
6.42±0.50(Predicted) | [color ]
white to brown | [InChIKey]
LETMYYZWCFHZLY-UHFFFAOYSA-N | [SMILES]
C12=NC(C3=CC=CC=C3)=CN1C=C(C4=CC=CC=C4)C=C2 |
| Safety Data | Back Directory | [WGK Germany ]
WGK 3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2 |
| Hazard Information | Back Directory | [Description]
GA11 inhibitor of ALDH1. It also shows anti-GBM effects in vitro and in vivo. | [Uses]
GA11 is an ALDH inhibitor that shows activity against glioblastoma both in vitro and in vivo[1]. | [References]
[1] Cheng P, et al. FOXD1-ALDH1A3 Signaling Is a Determinant for the Self-Renewal and Tumorigenicity of Mesenchymal Glioma Stem Cells. Cancer Res. 2016 Dec 15;76(24):7219-7230. DOI:10.1158/0008-5472.CAN-15-2860 |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|