| Identification | Back Directory | [Name]
BenzaMide, 4-[(3,3-diMethyl-1-oxobutyl)aMino]-3,5-difluoro-N-2-thiazolyl- | [CAS]
851202-49-8 | [Synonyms]
LuAA41063
Lu-AA41063
Lu AA41063
Lu AA-41063
Lu AA 41063
4-(3,3-dimethylbutanoylamino)-3,5-difluoro-N-(1,3-thiazol-2-yl)benzamide
BenzaMide, 4-[(3,3-diMethyl-1-oxobutyl)aMino]-3,5-difluoro-N-2-thiazolyl- | [Molecular Formula]
C16H17F2N3O2S | [MDL Number]
MFCD18642660 | [MOL File]
851202-49-8.mol | [Molecular Weight]
353.387 |
| Hazard Information | Back Directory | [Description]
Lu AA41063 is a potent and selective hA2A receptor antagonist. | [Uses]
Lu AA41063 is an adenosine A2A receptor antagonist that may be useful in the treatment of Parkinson's disease. Lu AA41063 has a Ki value of 5.9 nM and targets the human A2A receptor. | [References]
[1] Selective degradation of polo‐like kinase 1 by a hydrophobically tagged inhibitor of the Polo‐box domain
[2] Discovery of novel polo-like kinase 1 polo-box domain inhibitors to induce mitotic arrest in tumor cells |
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