| Identification | Back Directory | [Name]
PYRIMIDIN-4-YLBORONIC ACID | [CAS]
852362-24-4 | [Synonyms]
4-Boronopyrimidine
PyriMidin-4-boronic acid
Pyrimidine-4-boronic acid
Pyrimidine-3-boronic acid
PYRIMIDIN-4-YLBORONIC ACID
Boronic acid,B-4-pyriMidinyl-
Pyrimidin-4-ylboronic Acid (~80%) | [Molecular Formula]
C4H5BN2O2 | [MDL Number]
MFCD08234611 | [MOL File]
852362-24-4.mol | [Molecular Weight]
123.91 |
| Chemical Properties | Back Directory | [Melting point ]
>205°C (dec.) | [Boiling point ]
334.7±34.0 °C(Predicted) | [density ]
1.33 | [storage temp. ]
Refrigerator, under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
6.86±0.53(Predicted) | [color ]
White to Off-White | [InChI]
InChI=1S/C4H5BN2O2/c8-5(9)4-1-2-6-3-7-4/h1-3,8-9H | [InChIKey]
YQEFFTJDRKXKAP-UHFFFAOYSA-N | [SMILES]
B(C1C=CN=CN=1)(O)O |
| Hazard Information | Back Directory | [Uses]
Pyrimidin-4-ylboronic Acid is an intermediate used to prepare aldosterone synthase inhibiting pyrimidinylnaphthalenes via Suzuki cross-coupling reactions. It is also used in the synthesis of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine as a potent, orally active Src kinase inhibitor with antitumor activity. |
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| Company Name: |
Cool Pharm, Ltd
|
| Telephone: |
021-60455363 18019463053 |
| Website: |
www.coolpharm.com |
| Company Name: |
Struchem Co., Ltd.
|
| Telephone: |
0512-63009836 18994340901 |
| Website: |
http://www.beidapharma.com |
| Company Name: |
parabiochem
|
| Telephone: |
025-83453382-8005 |
| Website: |
www.parabiochem.cn |
|