| Identification | Back Directory | [Name]
ME-143 | [CAS]
852536-39-1 | [Synonyms]
ME-143
NV-143
NADH oxidase inhibitor
ME143; ME 143; NV143; NV-143
3,4-bis(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-ol
2H-1-Benzopyran-7-ol, 3,4-dihydro-3,4-bis(4-hydroxyphenyl)- | [Molecular Formula]
C21H18O4 | [MOL File]
852536-39-1.mol | [Molecular Weight]
334.37 |
| Chemical Properties | Back Directory | [Boiling point ]
536.3±50.0 °C(Predicted) | [density ]
1.332±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
9.89±0.60(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
ME-143 is a second-generation tumor-specific inhibitor of NADH oxidase. ME-143 inhibits the WNT/β-catenin pathway in colorectal cancer cells. ME-143 has broadly active against cancers in vitro and in vivo[1]. | [References]
[1] Pintova S, et al. ME-143 Is Superior to Genistein in Suppression of WNT Signaling in Colon Cancer Cells. Anticancer Res. 2017;37(4):1647-1653. DOI:10.21873/anticanres.11495 |
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| Company Name: |
NCE Biomedical Co.,Ltd.
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| Tel: |
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15748/0_EN.htm |
| Company Name: |
SPIRO PHARMA
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| Tel: |
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| Website: |
www.spiropharma.com.cn |
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