| Identification | Back Directory | [Name]
WAY-652291 | [CAS]
854137-39-6 | [Synonyms]
WAY-652291
BETbromodomaininhibitor3
1,3-Dimethyl-5-(p-tolyl)-5,9-dihydrofuro[3',4':5,6]pyrido[2,3-d]pyrimidine-2,4,6(1H,3H,8H)-trione
1,3-dimethyl-5-(p-tolyl)-8,9-dihydrofuro[3',4':5,6]pyrido[2,3-d]pyrimidine-2,4,6(1H,3H,5H)-trione
1,3-Dimethyl-5-(p-tolyl)-5,9-dihydrofuro[3',4':5,6]pyrido[2,3-d]pyrimidine-2,4,6(1H,3H,8H)-trione
1,3-dimethyl-5-(p-tolyl)-8,9-dihydrofuro[3',4':5,6]pyrido[2,3-d]pyrimidine-2,4,6(1H,3H,5H)-trione | [Molecular Formula]
C18H17N3O4 | [MOL File]
854137-39-6.mol | [Molecular Weight]
339.35 |
| Chemical Properties | Back Directory | [Melting point ]
294-296 °C (decomp) | [Boiling point ]
570.664±60.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.450±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
1.351±0.40(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
BET bromodomain inhibitor 3 is BET bromodomain inhibitor. BET bromodomain inhibitor 3 has inhibitory effect against BrdT with Ki value of > 40 μM. BET bromodomain inhibitor 3 can be used for the research of contraception, cancer, and heart disease[1]. | [References]
[1] Ayoub AM, et al. BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen [published correction appears in J Med Chem. 2017 Jul 27;60(14):6458]. J Med Chem. 2017;60(12):4805-4817. DOI:10.1021/acs.jmedchem.6b01336 |
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