| Identification | Back Directory | [Name]
FUREGRELATE | [CAS]
85666-24-6 | [Synonyms]
FUREGRELATE
Furegrelato
Furegarelatum
Unii-kx4D9bza6x
Furegrelate [inn]
Furegrelato [spanish]
Furegarelatum [latin]
5-(3-Pyridylmethyl)benzofuran-2-carboxylic acid
2-Benzofurancarboxylic acid, 5-(3-pyridinylmethyl)-
5-(pyridin-3-ylmethyl)-1-benzofuran-2-carboxylic acid | [Molecular Formula]
C15H11NO3 | [MDL Number]
MFCD00868139 | [MOL File]
85666-24-6.mol | [Molecular Weight]
253.25 |
| Hazard Information | Back Directory | [Uses]
Inhibitor (thromboxane synthetase). | [Definition]
ChEBI: 5-(3-pyridinylmethyl)-2-benzofurancarboxylic acid is a member of benzofurans. | [in vivo]
Furegrelate (1-5 mg/kg; po) prevents blockage of the coronary artery[1].
Furegrelate (0.1-5 mg/kg; i.v.) prevents the blockage of stenosed coronary arteries caused platelet aggregation[1].
Furegrelate blunts the development of hypoxia-induced pulmonary arterial hypertension (PAH) in an established neonatal piglet model primarily by preserving the structural integrity of the pulmonary vasculature[2].
Furegrelate has a long half-life compared to several other drugs used to treat PAH, including nitric oxide and prostagcyclin analogues; And Furegrelate is highly specific to the target enzyme[2]. |
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Leancare Ltd.
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+33 962096793 |
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www.leancare.co.uk |
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