| Identification | Back Directory | [Name]
(+/-)-2-AMINO-7-PHOSPHONOHEPTANOIC | [CAS]
85797-13-3 | [Synonyms]
Brn 3544152
2-amino-7-phosphono-heptanoicaci
(+/-)-2-AMINO-7-PHOSPHONOHEPTANOIC
Heptanoic acid, 2-amino-7-phosphono- | [Molecular Formula]
C7H16NO5P | [MDL Number]
MFCD00055057 | [MOL File]
85797-13-3.mol | [Molecular Weight]
225.18 |
| Hazard Information | Back Directory | [Uses]
DL-AP7 is a competitive NMDA antagonist and an anticonvulsant. DL-AP7 blocks the NMDA-induced convulsions and impairs learning performance in a passive avoidance task in mice[1]. | [in vivo]
DL-AP7 (ICV) blocks the NMDA-induced convulsions (ED50=0.22 nmol/mouse) and impairs learning performance in a passive avoidance task in mice[1]. | [IC 50]
NMDA Receptor | [References]
[1] Chiamulera C, et al. Effect of NMDA- and strychnine-insensitive glycine site antagonists on NMDA-mediated convulsions and learning. Psychopharmacology (Berl). 1990;102(4):551-552. DOI:10.1007/BF02247140 |
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