| Identification | Back Directory | [Name]
cefaloram | [CAS]
859-07-4 | [Synonyms]
cefaloram
Cephalosporin G
(7R)-7-(Phenylacetylamino)-3-(acetoxymethyl)cepham-3-ene-4-carboxylic acid
(7R)-3-(Acetoxymethyl)-7β-[(α-oxophenethyl)amino]cepham-3-ene-4-carboxylic acid
(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-[(phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-3-(acetoxymethyl)-8-keto-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-(2-phenylethanoylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-8-oxo-7-[(2-phenylacetyl)amino]-, (6R,7R)- | [EINECS(EC#)]
212-725-1 | [Molecular Formula]
C18H18N2O6S | [MOL File]
859-07-4.mol | [Molecular Weight]
390.41 |
| Chemical Properties | Back Directory | [Melting point ]
160-162 °C (decomp) | [Boiling point ]
742.8±60.0 °C(Predicted) | [density ]
1.48±0.1 g/cm3(Predicted) | [pka]
2.68±0.50(Predicted) |
| Hazard Information | Back Directory | [Definition]
ChEBI: Cefaloram is a cephalosporin derivative with potent antibacterial activity which binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division, inactivation of which interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity, resulting in the weakening of the bacterial cell wall and causing cell lysis. It has a role as an antibacterial drug. |
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