| Identification | Back Directory | [Name]
N-[(5Z)-5-[(E)-3-(furan-2-yl)prop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzenesulfonamide | [CAS]
861123-84-4 | [Synonyms]
Benzenesulfonamide, N-[5-[3-(2-furanyl)-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidinyl]-
CU-3 5-(3-(2-Furyl)prop-2-enylidene)-3-
[(phenylsulfonyl)amino]-2-thioxo-1,3-thiazolidin-4-one
N-[(5Z)-5-[(E)-3-(furan-2-yl)prop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzenesulfonamide | [Molecular Formula]
C16H12N2O4S3 | [MDL Number]
MFCD07197018 | [MOL File]
861123-84-4.mol | [Molecular Weight]
392.47 |
| Hazard Information | Back Directory | [Description]
CU-3 is a novel potent and selective diacylglycerol kinase alpha (DGKalpha) inhibitor, attenuating cancer cell proliferation and simultaneously enhancing immune responses including anti-cancer immunity. | [Uses]
(E/Z)-CU-3 is a MCL-1 modulator. (E/Z)-CU-3 can be used to study hyperproliferative diseases, angiogenic diseases, cell cycle regulation diseases, autophagy regulation diseases, inflammatory diseases and/or infectious diseases[1]. | [References]
[1] Loren D, et al. Small molecules for the modulation of mcl-1 and methods of modulatiing cell death, cell division, cell differentiation and methods of treating disorders. WO2011094708A2. WIPO. 2011-01-31. |
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