| Identification | Back Directory | [Name]
5'-Fluoro-1H,1'H-[2,3']biindolylidene-3,2'dione3-oxime | [CAS]
861214-33-7 | [Synonyms]
5'-FIO
-Fluoroindirubinoxime
5'-Fluoroindirubinoxime
5'-Fluoro-1H,1'H-[2,3']biindolylidene-3,2'dione3-oxime
2H-Indol-2-one, 3-[1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-5-fluoro-1,3-dihydro- | [Molecular Formula]
C16H10FN3O2 | [MDL Number]
MFCD18086923 | [MOL File]
861214-33-7.mol | [Molecular Weight]
295.27 |
| Chemical Properties | Back Directory | [Boiling point ]
528.3±50.0 °C(Predicted) | [density ]
1.57±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Store in freezer, under -20°C | [solubility ]
DMSO : 83.33 mg/mL (282.22 mM; Need ultrasonic) | [form ]
Powder | [pka]
8.48±0.20(Predicted) | [color ]
Light brown to black |
| Hazard Information | Back Directory | [Uses]
5’-Fluoroindirubinoxime is an antiproliferative agent and an inhibitor of FLT3. | [in vivo]
5'-Fluoroindirubinoxime (5’-FIO, 10 μmol/L/100 μL (~2.95 mg/mL) every other day beginning on day 6, S.C..) exhibits significant anti-tumor activity in rats[2]. | Animal Model: | Rat tumor model based RK3E-ras cells[2]. | | Dosage: | S.C.. | | Administration: | 10 μmol/L/100 μL (~2.95 mg/mL) every other day beginning on day 6. | | Result: | Effectively inhibited tumor growth. |
| [storage]
Store at -20°C |
|
| Company Name: |
BOC Sciences
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1-631-485-4226; 16314854226 |
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https://www.bocsci.com |
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cjbscvictory
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13348960310 |
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https://www.weikeqi-biotech.com/ |
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