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861224-28-4

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861224-28-4 Structure

861224-28-4 Structure
IdentificationBack Directory
[Name]

Shepherdin
[CAS]

861224-28-4
[Synonyms]

Shepherdin
[Molecular Formula]

C41H64N12O12S
[MDL Number]

MFCD32068002
[MOL File]

861224-28-4.mol
[Molecular Weight]

949.085
Chemical PropertiesBack Directory
[Boiling point ]

1501.2±65.0 °C(Predicted)
[density ]

1.333±0.06 g/cm3(Predicted)
[pka]

3.40±0.10(Predicted)
[Sequence]

Lys-His-Ser-Ser-Gly-Cys-Ala-Phe-Leu
Hazard InformationBack Directory
[Uses]

Shepherdin (79-87) is amino acids 79 to 87 fragment of Shepherdin. Shepherdin is a peptidomimetic antagonist of the complex between Hsp90 and Survivin. Anticancer activity[1].
[IC 50]

HSP90; Survivin
[References]

[1] Plescia J, et al. Rational design of shepherdin, a novel anticancer agent. Cancer Cell. 2005 May;7(5):457-68. DOI:10.1016/j.ccr.2005.03.035
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