| Identification | Back Directory | [Name]
1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-2-methyl-5-(phenylmethyl)- | [CAS]
863004-48-2 | [Synonyms]
WAY-333184
5-Benzyl-2-methyl-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one
1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-2-methyl-5-(phenylmethyl)- | [Molecular Formula]
C17H17NOS | [MOL File]
863004-48-2.mol | [Molecular Weight]
283.39 |
| Chemical Properties | Back Directory | [Boiling point ]
499.1±44.0 °C(Predicted) | [density ]
1.184±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
0.86±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
GSK-3β inhibitor 14 (Compound 6i), benzothiazepinone derivative, is a weak GSK-3β inhibitor (IC50 >100 μM)[1]. | [References]
[1] Zhang P, et al. Design, synthesis and biological evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β). Eur J Med Chem. 2013 Mar;61:95-103. DOI:10.1016/j.ejmech.2012.09.021 |
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