| Identification | Back Directory | [Name]
L 645151 | [CAS]
86394-94-7 | [Synonyms]
L 645151
2,2-Dimethylpropanoic acid 2-(aminosulfonyl)benzothiazol-6-yl ester | [Molecular Formula]
C12H14N2O4S2 | [MOL File]
86394-94-7.mol | [Molecular Weight]
314.38 |
| Hazard Information | Back Directory | [Description]
L 645151 is a lipophilic CA inhibitor. | [Uses]
L-645151 is a carbonic anhydrase inhibitor with ocular penetration and hypotensive activity. L-645151 lowers the elevated intraocular pressure (IOP) of o-chymotripsinized (o-CT) rabbit eyes. L-645151 is promising for research of an ocular hypotensive agent[1]. | [References]
[1] Bar-Ilan A, et al. Ocular penetration and hypotensive activity of the topically applied carbonic anhydrase inhibitor L-645,151. J Ocul Pharmacol. 1986 Spring;2(2):109-20. DOI:10.1089/jop.1986.2.109 |
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