| Identification | Back Directory | [Name]
4-(3-Bromophenyl)-2,6-diphenylpyrimidine | [CAS]
864377-28-6 | [Synonyms]
3-BTPPM
4-(3-Bromophenyl)-2,6-diphenylpyrimidine
Pyrimidine, 4-(3-bromophenyl)-2,6-diphenyl-
4-(3-Bromophenyl)-2,6-diphenylpyrimidine > | [Molecular Formula]
C22H15BrN2 | [MDL Number]
MFCD28962150 | [MOL File]
864377-28-6.mol | [Molecular Weight]
387.272 |
| Chemical Properties | Back Directory | [Melting point ]
134.0 to 138.0 °C | [Boiling point ]
450℃ | [density ]
1.345 | [Fp ]
226℃ | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
powder to crystal | [pka]
0.41±0.30(Predicted) | [color ]
White to Almost white |
| Hazard Information | Back Directory | [Synthesis]
a) Suspend 5.45 g (34.8 mmol) benzenecarboximidamide hydrochloride hydrate and 4.10 g (73.1 mmol) potassium carbonate in 50 mL of ethanol at 90 °C with stirring in an atmosphere of dry air. Slowly 20.0 g (69.7 mmol) of (E)-1-(3-bromophenyl)-3-phenylprop-2-en-1-one dissolved in 20 mL of hot ethoxyethanol was added dropwise. After 24 hours of reaction, the mixture was cooled to 25 °C, the solid product was collected by filtration and washed sequentially with ethanol, water and ethanol, the resulting crude product was used directly in step b) without further purification. | [References]
[1] Patent: WO2012/80052, 2012, A1. Location in patent: Page/Page column 48
[2] Patent: US2012/149904, 2012, A1. Location in patent: Page/Page column 43 |
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