| Identification | Back Directory | [Name]
(S)-1-(5-PHENYL-1H-IMIDAZOL-2-YL)ETHANAMINE | [CAS]
864825-23-0 | [Synonyms]
EOS-61915
Imidazole-2-methanamine
Eluxadoline Intermediate 4
1-(4-phenyl-1H-imidazol-2-yl)-ethylamine
(S)-1-(4-phenyl-1H-imidazol-2-yl)ethanamine
(S)-1-(5-PHENYL-1H-IMIDAZOL-2-YL)ETHANAMINE
(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethanamine
(S)-[1-(4-Phenyl-1H-imodazol-2-yl)-ethanamine
(alpha)-α-Methyl-4-phenyl-1H-imidazole-2-methanamine
1H-Imidazole-2-methanamine, α-methyl-4-phenyl-, (αS)-
1H-Imidazole-2-methanamine, α-methyl-5-phenyl-, (αS)-
(S)-alpha-Methyl-4-phenyl-1H
-imidazole-2-methanamine
(alphaS)-alpha-Methyl-4-phenyl-1H-imidazole-2-methanamine
Eluxadoline: (alphaS)-alpha-Methyl-4-phenyl-1H-imidazole-2-methanamine | [EINECS(EC#)]
1592732-453-0 | [Molecular Formula]
C11H13N3 | [MDL Number]
MFCD11846157 | [MOL File]
864825-23-0.mol | [Molecular Weight]
187.245 |
| Chemical Properties | Back Directory | [Melting point ]
136-138°C | [Boiling point ]
422.1±28.0 °C(Predicted) | [density ]
1.145±0.06 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
13.16±0.10(Predicted) | [color ]
PaleYellow | [InChI]
InChI=1/C11H13N3/c1-8(12)11-13-7-10(14-11)9-5-3-2-4-6-9/h2-8H,12H2,1H3,(H,13,14)/t8-/s3 | [InChIKey]
XQFMQMXJXWTGON-SBYBRXNCNA-N | [SMILES]
[C@H](C1NC(C2=CC=CC=C2)=CN=1)(N)C |&1:0,r| |
| Hazard Information | Back Directory | [Description]
(S)-1-(4-Phenyl-1H-imidazol-2-yl)ethanamine is a pharmaceutical intermediate ingredient used in the preparation of Eluxadoline drugs for the treatment of adults suffering from irritable bowel syndrome with diarrhoea (IBS-D). | [Uses]
(S)-1-(4-Phenyl-1H-imidazol-2-yl)ethanamine is an intermediate used to prepare a δ-opioid antagonists/μ-opioid agonists used in potential therapy for diarrhea-predominant irritable bowel syndrome (IBS-d). |
|
|