| Identification | Back Directory | [Name]
BMS 663068 (Tris) | [CAS]
864953-39-9 | [Synonyms]
BMS663068 (Tris)
Fostemsavir Tris
BMS 663068 (Tris)
BMS-663068 (Tris)
Fostemsavir tromethamine
Fostemsavir Tris (BMS-663068 Tris)
BMS663068 (TRIS); BMS 663068 (TRIS)
Fostemsavir Tris (BMS-663068 trisaminomethane)
Inhibitor,inhibit,BMS 663068,BMS663068,HIV,Human immunodeficiency virus,Fostemsavir,BMS-663068,Fostemsavir Tris | [Molecular Formula]
C29H37N8O11P | [MOL File]
864953-39-9.mol | [Molecular Weight]
704.625 |
| Hazard Information | Back Directory | [Uses]
Fostemsavir Tris (BMS-663068 (Tris)) is the phosphonooxymethyl proagent of BMS-626529. Fostemsavir Tris (BMS-663068 (Tris)) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells. | [in vivo]
Fostemsavir Tris has good antiviral activity in subjects infected with virus shown to be susceptible (IC50, <100 nM) to the agent[1]. | [IC 50]
HIV-1 | [storage]
Store at -20°C | [References]
[1] Nowicka-Sans B, et al. In vitro antiviral characteristics of HIV-1 attachment inhibitor BMS-626529, the active component of the prodrug BMS-663068. Antimicrob Agents Chemother. 2012 Jul;56(7):3498-507. DOI:10.1128/AAC.00426-12 |
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| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
|