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865200-20-0

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865200-20-0 Structure

865200-20-0 Structure
IdentificationBack Directory
[Name]

GIRIPLADIB
[CAS]

865200-20-0
[Synonyms]

PLA 695
GIRIPLADIB
NHHBNHIPCSPSHQ-UHFFFAOYSA-N
4-[3-[1-benzhydryl-5-chloro-2-[2-[[2-(trifluoromethyl)phenyl]methylsulfonylamino]ethyl]indol-3-yl]propyl]benzoic acid
4-(3-[5-Chloro-1-(diphenylmethyl)-2-[2-(((2-(trifluoromethyl)benzyl)sulfonyl)amino)ethyl]-1H-indole-3-yl]propyl)benzoic acid
Benzoic acid, 4-[3-[5-chloro-1-(diphenylMethyl)-2-[2-[[[[2-(trifluoroMethyl)phenyl]Methyl]sulfonyl]aMino]ethyl]-1H-indol-3-yl]propyl]-
[Molecular Formula]

C41H36ClF3N2O4S
[MDL Number]

MFCD11973646
[MOL File]

865200-20-0.mol
[Molecular Weight]

745.25
Chemical PropertiesBack Directory
[Boiling point ]

852.6±75.0 °C(Predicted)
[density ]

1.29
[form ]

Solid
[pka]

4.34±0.10(Predicted)
[color ]

White to light yellow
Hazard InformationBack Directory
[Uses]

Giripladib inhibits cytosolic phospholipase A2 (cPLA2) which in turn radiosensitizes tumors in lung cancer animal models.
[Uses]

Treatment of pain and symptomatic management of arthritis.
[IC 50]

cPLA2α
Spectrum DetailBack Directory
[Spectrum Detail]

GIRIPLADIB(865200-20-0)1HNMR
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